Paraquat Induced Toxicity in Adrenals in Albino Mice
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چکیده
منابع مشابه
Paraquat Induced Toxicity in Adrenals in Albino Mice
Objectives: The current study aims to observe the histological effects of paraquat on the adrenal Glands of the mice after single exposure to sub-lethal dose of the drug. Materials and Method: Forty male mice, fifteen control (group I) and twenty-five experimental (group II) were used. Each experimental animal (group II) was given a single dose of paraquat i.e 20 mg/kg dissolved in 0.2 ml norma...
متن کاملATTENUATION OF PARAQUAT TOXICITY IN MICE
Paraquat (PQ) is a widely used herbicide. However, a large number of cases of accidental or suicidal poisoning from PQ has been reported. Membrane damage induced by lipid peroxidation, inactivation of protein or damage to DNA by radical formation have been suggested as toxicity mechanisms of PQ. In the present work, the effects of atropine, propranolol, procainamide and dipyridamole on PQ-...
متن کاملattenuation of paraquat toxicity in mice
paraquat (pq) is a widely used herbicide. however, a large number of cases of accidental or suicidal poisoning from pq has been reported. membrane damage induced by lipid peroxidation, inactivation of protein or damage to dna by radical formation have been suggested as toxicity mechanisms of pq. in the present work, the effects of atropine, propranolol, procainamide and dipyridamole on pq-induc...
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Background: Lutein, a carotenoid compound, has previously been studied for its antioxidant and medicinal properties as well as the moderate protection it confers against gamma radiation. This study aimed at evaluating the effects of lutein against radiation-induced hematological and biochemical changes in mice.Methods: The optimized dose of the compound was orally administered for 15 days, and ...
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Acute toxicity study of potassium permanganate was carried out in Swiss albino mice. Potassium permanganate was administered at dose rate of 0.0, 500, 1000, 1500, 2000, 2500, 3000 and 3500mg/kg body weight to groups 1, 2, 3, 4, 5, 6, 7 and 8, ten per group for LD50 determination. The dead animals were posted for gross lesions. A predetermined dose of 160mg/kg of the chemical was administered to...
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ژورنال
عنوان ژورنال: American Journal of Biomedical Sciences
سال: 2011
ISSN: 1937-9080
DOI: 10.5099/aj110300229